E2S1 DHPT shouldn't matter for any case that's not plight AA. I did both Aquila and Lygus 0c sustainless. infi ult from Cyrene should help with not needing sustain unless enemies start hitting way harder very soon.
https://preview.redd.it/q6pjurokcf0g1.png?width=425&format=png&auto=webp&s=e9d9c7bd30cbb9c764713127a833c4cee6f2b90e